We would like to inform you that the HOVON Data Center (HDC) and the HOVON Safety Desk will remain fully operational to ensure the safety of the patients included in HOVON trials.

The distribution and delivery of the study medicinal products are being closely monitored and we will inform you accordingly if any actions need to be taken.

The central laboratories are also still fully functioning.

At the moment it is possible to include patients in all active HOVON trials.


Participating sites:

Please make sure to inform the HOVON Data Center per e-mail ( if your hospital has decided to temporarily halt patient inclusion in clinical trials following the COVID-19 outbreak.

In case patient visits or study procedures cannot be performed per protocol due to the COVID-19, please document this in the patient files.



Given the situation surrounding the Corona virus, the HOVON central Office (HCB) and the HOVON Data Center (HDC) are temporarily unavailable by phone.

Please send all (urgent) question via email, these will be picked up and processed by the team as soon as possible. We hope for your understanding of this situation.

For study specific questions, you can contact the concerning HOVON Trial Manager or our general e-mail address ( - Please include HOVON study number as reference). Thank you for your cooperation.


HOVON Central Office (HCB):

HOVON Data Center (HDC):


With kind regards, Marleen Breems (HOVON General Director) and Bianca Backx (manager HDC)

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HOVON Policy documents


Below you can find the policy documents of the HOVON.

Please note, some of the documents can only be viewed after you are logged in and click on the protected policies tab in the menu.


HOVON Policy Data and Safety Monitoring Board

HOVON Policy Collaboration in international trials

HOVON Policy Duration of Follow Up

HOVON Policy Electronic source documents

HOVON Policy ICF version control

HOVON Policy Publications

HOVON Policy Audits and inspections

HOVON Policy Site selection

HOVON Policy Premature termination of a trial or investigational site

HOVON Policy Initiating a HOVON trial

Guideline for initiating a HOVON trial

HOVON Policy Investigator terminology

HOVON Policy Data confidentiality

HOVON Policy Dutch Hematopoietic Stem Cell Transplantation Registry

HOVON Policy Development of treatment guidelines by HOVON

HOVON Policy PI responsibilities and qualifications

HOVON Policy Echelon classification

HOVON Policy Trial data collection

HOVON Policy Local Investigator responsibilities

HOVON Policy Risk Based Quality Management of Clinical Trials

HOVON Policy Development and Management of HOVON Policies

HOVON Policy Biobanking

Request / template formulieren

Template for request data from HOVON trials.pdf

Template for request data from HOVON trials.doc

Template for recording delegation of HOVON sponsor responsibilities.pdf

Template for recording delegation of HOVON sponsor responsibilities.doc

Template for HOVON Principal Investigator Training Record.pdf

Template for Quality Risk Management Plan.pdf

Template for Quality Risk Management Plan.doc

Template for request samples from HOVON biobank.pdf

Template for request samples from HOVON biobank.doc

Template for HOVON Project Proposal form.doc