We would like to inform you that the HOVON Data Center (HDC) and the HOVON Safety Desk will remain fully operational to ensure the safety of the patients included in HOVON trials.

The distribution and delivery of the study medicinal products are being closely monitored and we will inform you accordingly if any actions need to be taken.

The central laboratories are also still fully functioning.

At the moment it is possible to include patients in all active HOVON trials.


Participating sites:

Please make sure to inform the HOVON Data Center per e-mail ( if your hospital has decided to temporarily halt patient inclusion in clinical trials following the COVID-19 outbreak.

In case patient visits or study procedures cannot be performed per protocol due to the COVID-19, please document this in the patient files.



Given the situation surrounding the Corona virus, the HOVON central Office (HCB) and the HOVON Data Center (HDC) are temporarily unavailable by phone.

Please send all (urgent) question via email, these will be picked up and processed by the team as soon as possible. We hope for your understanding of this situation.

For study specific questions, you can contact the concerning HOVON Trial Manager or our general e-mail address ( - Please include HOVON study number as reference). Thank you for your cooperation.


HOVON Central Office (HCB):

HOVON Data Center (HDC):


With kind regards, Marleen Breems (HOVON General Director) and Bianca Backx (manager HDC)

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Studies SCT (Stem Cell Transplantation and Cellular Therapies)

Study name Status Echelon level Stage Age Updated Included patients Active sites
HOVON-associated TARGET study Open Level A - >= 18 01-04-2019 n/a n/a
HOVON-associated PLMA25 NK-cell study Closed n/a - >= 55 29-09-2015 n/a n/a
HOVON-associated Innate allo-SCT Closed n/a - >18 19-11-2018 n/a n/a
HOVON-associated Anti-CD20 cGVHD study Closed n/a - >=18 09-12-2015 n/a n/a
HOVON-associated CMV pp65 specific T-cells Open n/a - 0 - 75 18-10-2012 n/a n/a
HOVON 115 Double UCBT Closed Level A - 03-05-2018 70 6
HOVON 113 MSC Closed Level A, Level B 2nd line Any age 04-11-2019 42 8
HOVON 112 MSC On hold Level A 1st line Any age 03-05-2018 39 2
HOVON 107 MOBILIZATION Closed Level A - 18-60 07-12-2018 38 4
HOVON 106 DOUBLE UCBT Closed n/a - 18-65 03-05-2018 41 5
HOVON 96 GVHD Closed n/a 1st line 18 - 70 13-11-2019 494 7