HOVON HO36 MM

Archived

Main info

Identifier:
HO36 MM
Sponsor:
HOVON
Included patients:
72
Active sites:
46
(of 46)
Title:

A study of the efficacy, morbidity and quality of life of the standard treatment with Melphalan and Prednison versus an intensified treatment in elderly patients with Multiple Myeloma: A Phase III study.

Timeline

Scheduled
Actual
1997
01 Nov
Opportunity
1997
11 Nov
Activated
1999
11 Nov
ClosedForInclusionActualStart
2009
11 Nov
Archived

Flow

Flow

Details

Phase:
Select:
Monitoring Type:
Objectives:

Eligibility

Inclusion Criteria:
  • Patients with multiple myeloma not yet treated with chemotherapy.
  • Age > 64
  • WHO performance status 0, 1, 2 or 3.
  • Salmon and Durie stages Ib, IIa, IIb, IIIa and IIIb.
  • A well-measurable tumor parameter.
Exclusion Criteria:
  • Severe cardiac, pulmonary or hepatic disease.
  • Dependency on kidney function replacement therapy.
  • Previously treated with cytostatics and/or alpha-interferon.
  • A history of second primary malignant disease other than stage I carcinoma of the cervix and non-melanomatic cancer of the skin.

Participating Sites

Site
46 results
Order by
Accrual rate
Activation date
NL-Amsterdam-OLVG
7
NL-Den Haag-HAGA
7
NL-Breda-AMPHIA
5
NL-Amersfoort-MEANDERMC
5
NL-Hilversum-TERGOOI
4
NL-Zwolle-ISALA
3
NL-Leiden-LUMC
3
NL-Amsterdam-SLOTERVAART
3
NL-Rotterdam-ERASMUSMC
3
NL-Nieuwegein-ANTONIUS
3
NL-Leeuwarden-MCL
3
NL-Den Bosch-JBZ
2
NL-Roosendaal-BRAVIS
2
NL-Amsterdam-BOVENIJ
2
NL-Deventer-DZ
2
NL-Utrecht-UMCUTRECHT
2
NL-Amsterdam-AMC
2
NL-Delfzijl-OMMELANDERDELFZIJL
1
NL-Emmen-SCHEPER
1
NL-Drachten-NIJSMELLINGHE
1
NL-Leiderdorp-ALRIJNELEIDERDORP
1
NL-Eindhoven-CATHARINA
1
NL-Heerlen-ATRIUMMC
1
NL-Hengelo-ZGTHENGELO
1
NL-Stadskanaal-TRENTREFAJA
1
NL-Maastricht-MUMC
1
NL-Tilburg-ETZ
1
NL-Vlaardingen-VLIETLANDVLARDINGEN
1
NL-Tilburg-TWEESTEDEN
NL-Leiden-ALRIJNLEIDEN
NL-Utrecht-DIAKONESSENUTRECHT
NL-Rotterdam-SFG
NL-Veghel-BERNHOVENVEGEL
NL-Spijkenisse-SPIJKENISSEMC
NL-Zaandam-ZAANSMC
NL-Rotterdam-MAASSTADZIEKENHUIS
NL-Groningen-UMCG
NL-Hoofddorp-SPAARNEGASTHUIS
NL-Schiedam-FRANCISCUSVLIETLAND
NL-Nijmegen-RADBOUDUMC
NL-Goes-ADRZ
NL-Enschede-MST
NL-Dirksland-VANWEELBETHESDA
NL-Leidschendam-HMCANTONIUSHOVE
NL-Amsterdam-VUMC
NL-Sittard-Geleen-ZUYDERLAND
= Active hospitals
= Inactive hospitals

Participating Parties

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