LLPC working group




Prof. M.J. Kersten (AmsterdamUMC – AMC, Amsterdam)


Prof. M.C. Minnema (UMC Utrecht, Utrecht)


Dr P. Mutsaers (ErasmusMC, Rotterdam)

Key objectives of working group

The key objectives of this working group are:

  • The objective of the consortium is to actively contribute to the implementation of so-called “first-in-man” / phase I-II studies in malignant diseases of the blood, bone marrow and lymph nodes. Initially, Non-Hodgkin's lymphoma (B and T cell), Hodgkin's lymphoma and chronic lymphocytic leukemia (CLL) were chosen. Promising new drugs can then be incorporated in phase III studies, which are placed in the HOVON Lymphoma and CLL Working Groups. This creates the perspective to operate in the front line in HOVON with regard to the treatment of lymphomas and CLL.
  • Secondly, the accumulated expertise can be used to promote first-in-man trials / phase I-II studies in other hematological malignancies in collaboration with the respective HOVON Working Groups.
  • For the time being, it is expected that there will mainly be industry-sponsored trials. Ultimately, the goal is also to develop investigator-initiated studies. The working group will assess the relevance and feasibility of each study offered through one of its members or by industry. If it is decided to participate in the study, it will be determined by mutual agreement how many and which centers will participate.

The Lunenburg Lymphoma Phase 1 / II Consortium (LLPC) was founded in 2009 by 5 departments of Hematology of Dutch (academic) hospitals. Currently, the participating hospitals are:

  • Academic Medical Center (AmsterdamUMC - AMC), Amsterdam
  • Free University Medical Center (AmsterdamUMC - VUMC), Amsterdam
  • Erasmus Medical Center, Rotterdam
  • University Medical Center Groningen (UMCG), Groningen
  • University Medical Center Nijmegen (UMCN), Nijmegen
  • University Medical Center Utrecht (UMCU), Utrecht
  • St. Antonius Hospital, Nieuwegein
  • Leiden University Medical Center (LUMC), Leiden
  • Maastricht University Medical Center (MUMC), Maastricht

Publication overview

Meetings & Minutes

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