HOVON HO36 MM
Gearchiveerd
Main info
- Identificatie:
- HO36 MM
- Sponsor:
- HOVON
- Included patients:
-
72
- Active sites:
-
46(of 46)
- Title:
A study of the efficacy, morbidity and quality of life of the standard treatment with Melphalan and Prednison versus an intensified treatment in elderly patients with Multiple Myeloma: A Phase III study.
Timeline
Scheduled
Actual
1997
01 nov.
Opportunity
1997
11 nov.
Activated
1999
11 nov.
ClosedForInclusionActualStart
2002
30 jan.
Closeout in Progress
2009
11 nov.
Archived
2017
30 jan.
Destruction
Flow

Details
- Phase:
- Select:
- Monitoring Type:
- Objectives:
Eligibility
- Inclusion Criteria:
- Patients with multiple myeloma not yet treated with chemotherapy.
- Age > 64
- WHO performance status 0, 1, 2 or 3.
- Salmon and Durie stages Ib, IIa, IIb, IIIa and IIIb.
- A well-measurable tumor parameter.
- Exclusion Criteria:
- Severe cardiac, pulmonary or hepatic disease.
- Dependency on kidney function replacement therapy.
- Previously treated with cytostatics and/or alpha-interferon.
- A history of second primary malignant disease other than stage I carcinoma of the cervix and non-melanomatic cancer of the skin.
Participating Sites
Site
46 results
Order by
Accrual rate
Activation date
NL-Amsterdam-OLVG
7
NL-Den Haag-HAGA
7
NL-Breda-AMPHIA
5
NL-Amersfoort-MEANDERMC
5
NL-Hilversum-TERGOOI
4
NL-Zwolle-ISALA
3
NL-Leiden-LUMC
3
NL-Amsterdam-SLOTERVAART
3
NL-Rotterdam-ERASMUSMC
3
NL-Nieuwegein-ANTONIUS
3
NL-Leeuwarden-MCL
3
NL-Den Bosch-JBZ
2
NL-Roosendaal-BRAVIS
2
NL-Amsterdam-BOVENIJ
2
NL-Deventer-DZ
2
NL-Amsterdam-AMC
2
NL-Utrecht-UMCUTRECHT
2
NL-Eindhoven-CATHARINA
1
NL-Maastricht-MUMC
1
NL-Leiderdorp-ALRIJNELEIDERDORP
1
NL-Vlaardingen-VLIETLANDVLARDINGEN
1
NL-Hengelo-ZGTHENGELO
1
NL-Emmen-SCHEPER
1
NL-Heerlen-ATRIUMMC
1
NL-Drachten-NIJSMELLINGHE
1
NL-Tilburg-ETZ
1
NL-Delfzijl-OMMELANDERDELFZIJL
1
NL-Stadskanaal-TRENTREFAJA
1
NL-Veghel-BERNHOVENVEGEL
NL-Sittard-Geleen-ZUYDERLAND
NL-Spijkenisse-SPIJKENISSEMC
NL-Zaandam-ZAANSMC
NL-Tilburg-TWEESTEDEN
NL-Enschede-MST
NL-Rotterdam-MAASSTADZIEKENHUIS
NL-Groningen-UMCG
NL-Hoofddorp-SPAARNEGASTHUIS
NL-Schiedam-FRANCISCUSVLIETLAND
NL-Nijmegen-RADBOUDUMC
NL-Rotterdam-SFG
NL-Utrecht-DIAKONESSENUTRECHT
NL-Dirksland-VANWEELBETHESDA
NL-Goes-ADRZ
NL-Amsterdam-VUMC
NL-Leidschendam-HMCANTONIUSHOVE
NL-Leiden-ALRIJNLEIDEN